The Humane Society of the Ozarks' overall mission is to prevent cruelty to animals and to educate about responsible pet ownership. We achieve this goal through various programs, including education programs in local schools, spay/neuter assistance, emergency and shelter outreach, and cruelty prevention and investigation.

Executive Director - Carmen Nelson
Assistant Director - Shonna Harvey
Office Assistant - Jamey Sims

The Humane Society of the Ozarks, Inc. (HSO) has a Board of Directors that oversees the operation of the organization. The current Board of Directors for the HSO is as follows:
- Chris Blake - President
- Scott Hall - Vice President
- Melissa Owings - Secretary
- Kendyal Free - Treasurer
- LeAnn Box
- Stacey Fraser
- Linda Gaddy
- Georgia Granda
- Karen Koch
- Priscilla Kumpe
- Bonnie LaGrone
- Ronnie Robinson
- Jenny Shreve
- Joann Traw
- Amy White-Beard
- Steve Cochran
- Linda Taylor