The Humane Society of the Ozarks is a local, private, non-profit tax-exempt organization dedicated to the humane treatment of animals in Washington County and the surrounding region. The Society is funded by contributions from area individuals and businesses, grants, special fundraising events and the annual dues paid by its members.

The HSO played a major role in establishing, funding and upgrading the Fayetteville Animal Shelter, which is now funded by the City of Fayetteville. This shelter is considered by many to be one of the finest such facilities in the State of Arkansas.

 
The HSO's mission is "to promote the humane treatment of all animals". Supporting this mission, the HSO maintains that humans have a moral and legal responsibility to care for animals.

Additionally, the HSO actively promotes the spaying and neutering of companion animals and works cooperatively with other agencies to find long-term solutions to problems affecting animals in Northwest Arkansas.